Tardive Dyskinesia
About the Disease
Tardive Dyskinesia, also known as neuroleptic-induced tardive dyskinesia, is related to movement disease and parkinsonism, and has symptoms including spasmodic torticollis and myoclonus. An important gene associated with Tardive Dyskinesia is NQO1 (NAD(P)H Quinone Dehydrogenase 1), and among its related pathways/superpathways are Estrogen metabolism and Biogenic amine synthesis. The drugs Aripiprazole and Varenicline have been mentioned in the context of this disorder. Affiliated tissues include tongue, brain and globus pallidus, and related phenotypes are akathisia and tardive dyskinesia
Common Targets
G10280 | G3553 | Metabotropic glutamate (mGluR) receptor (nonspecified subtype) | G1132 | G23411 | G1128 | G3586 | G7498 | G10846 | G5770 | G6648 | G231 | G2932 | G1621 | G6532 | G3356 | G27185 | G2903 | P6348 | G2950 | G2567 | G1812 | beta-Adrenoceptor (nonspecified subtype) | G6833 | G3339 | G2548 | G412 | G497258 | sigma Receptor (nonspecified subtype) | Dopamine receptor (nonspecified subtype) | P2X Receptor (nonspecified subtype) | Nitric oxide synthase (NOS) (nonspecified subtype) | G6331 | G1814 | G886 | Inosine 5'-monophosphate dehydrogenase (IMPDH) (nonspecified subtype) | G1728 | G4988 | G1129 | G1956 | G5305 | G1813 | G627 | P6747 | G9312 | G207 | G6506 | G152 | G847 | G1312 | G4128 | G7124 | G148 | CCK receptor (nonspecified subtype) | G1565 | G6571 | G2332 | Kainate Receptor (GluR) (nonspecified subtype)
The "Target / Biomarker Review Report" is a comprehensive and customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about the Target(s) / Biomarker(s) of your choice related to Tardive Dyskinesia, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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